A loose screw on the drawing board does not only cause trouble. Eliot is also inspired to a new adventure with dog detective Ace. The opponent of the ingenious snoop is Screwie Louie. He is completely crazy and starts to turn all screws in the city. Ace does not just have to deal with the weird 'screwdriver'. Mafia boss Bugsy also wants to get involved and win Screwie for his followers. Ace starts a race against time.